[ luh-RAZ-uh-tohd ]

Larazotide acetate is an oral peptide that regulates tight junctions in the intestine. It works by binding to receptors on the top surface of intestinal cells, preventing the tight junctions from opening due to the presence of bacterial antigens, pro-inflammatory cytokines, or gluten-related peptides. Its mechanism of action has been confirmed through both laboratory and living organism studies.