Humanin

[ hyoo-MA-nin ]

Humanin is a mitochondrial peptide that is neuroprotective, cytoprotective, reduces inflammation, improves biomarkers related to lifespan.

Humanin is a small peptide, originally discovered in human cells, that's gained attention for its potential health benefits, particularly in relation to aging and cellular health. It’s produced naturally in the body and is encoded by the MT-RNR2 gene, which is located in the mitochondrial DNA.

Humanin helps protect cells from stress, oxidative damage, and inflammation, making it promising for conditions related to aging, neurodegenerative diseases (such as Alzheimer's), and metabolic disorders (such as type 2 diabetes), macular degeneration, and other eye issues. Humanin is also believed to support mitochondrial health, improve insulin sensitivity, and reduce cardiovascular risks.

Origin

Humanin was first discovered in 2001 in a study focused on understanding the role of mitochondrial dysfunction in age-related diseases. Unlike many other peptides, it’s encoded by the mitochondrial genome, and it has been found to have protective roles in various tissues.

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