Estradiol (E2)

Estradiol is a powerful and primary form of estrogen, which is a group of hormones primarily responsible for regulating various aspects of the female reproductive system and secondary sexual characteristics. It plays a central role in the development and maintenance of female reproductive organs and secondary sexual characteristics like breast development and body fat distribution.

Produced primarily in the ovaries, estradiol levels fluctuate throughout a woman's menstrual cycle, with the highest concentrations during the follicular phase when the ovaries are preparing to release an egg. It's crucial for regulating the menstrual cycle, supporting the growth and health of the uterine lining, and influencing fertility.

Estradiol is not exclusive to females; it is also present in smaller amounts in males, where it's produced by the testes and has functions such as supporting sperm production and bone health.

Beyond its reproductive roles, estradiol has effects on various tissues throughout the body, including bones, skin, and the cardiovascular system. It plays a crucial role in maintaining bone density, skin elasticity, and overall cardiovascular health.